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The 0.9% benzyl alcohol suppresses bacterial growth, which is what gives a reconstituted vial its ~28-day refrigerated shelf life

Psychoneuroendocrinology GLP-1 is both anxiogenic and antidepressant

These findings underscore the critical need for physicians to thoroughly assess patient history before prescribing GLP-1 RAs and highlight the urgent requirement for further prospective clinical trials to fully understand the implications of GLP-1 RA use on mental health in the obese patient population

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Tier 2 is less well-validated therapies and includes agents from tier 1 with the addition of pioglitazone and GLP-1 agonists